Toll-like-Rezeptor 1

Alexopoulou L et al. (2002) Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice.

Whitmore LC et al. (2016) A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.

Hart BE et al. (2012) Differential trafficking of TLR1 I602S underlies host protection against pathogenic mycobacteria.

West AP et al. (2011) TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

Schuring RP et al. (2009) Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions.

Misch EA et al. (2008) Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction.

Johnson CM et al. (2007) Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy.

Omueti KO et al. (2007) The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components.

Krutzik SR et al. (2003) Activation and regulation of Toll-like receptors 2 and 1 in human leprosy.

Kadowaki N et al. (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens.

Takeuchi O et al. (2002) Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.

Xu Y et al. (2000) Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.

Muzio M et al. (2000) Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells.

Rock FL et al. (1998) A family of human receptors structurally related to Drosophila Toll.

Taguchi T et al. (1996) Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

Nomura N et al. (1994) Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1.

Gay NJ et al. (1991) Drosophila Toll and IL-1 receptor.