Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel
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Cytochrom P450 2E1

Gentests:

Klinisch Untersuchungsmethoden Familienuntersuchung
Bearbeitungszeit 5 Tage
Probentyp genomische DNS
Klinisch Untersuchungsmethoden Hochdurchsatz-Sequenzierung
Bearbeitungszeit 25 Tage
Probentyp genomische DNS
Klinisch Untersuchungsmethoden Direkte Sequenzierung der proteinkodierenden Bereiche eines Gens
Bearbeitungszeit 25 Tage
Probentyp genomische DNS
Klinisch Untersuchungsmethoden Multiplex ligationsabhängige Amplifikation
Bearbeitungszeit 25 Tage
Probentyp genomische DNS

Verknüpfte Erkrankungen:

Referenzen:

1.

Wang SM et al. (2009) Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations.

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2.

Nebert DW et al. (1987) The P450 gene superfamily: recommended nomenclature.

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3.

Sun F et al. (1999) Association of genetic polymorphisms of alcohol-metabolizing enzymes with excessive alcohol consumption in Japanese men.

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4.

Sarmanová J et al. (2001) Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas.

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5.

None (1958) Pigments of rat liver microsomes.

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6.

None (1958) Studies on pig liver microsomes. I. Enzymic and pigment composition of different microsomal fractions.

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7.

OMURA T et al. (1962) A new cytochrome in liver microsomes.

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8.

Hayashi S et al. (1991) Genetic polymorphisms in the 5'-flanking region change transcriptional regulation of the human cytochrome P450IIE1 gene.

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9.

Watanabe J et al. (1990) PstI and RsaI RFLPs in complete linkage disequilibrium at the CYP2E gene.

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10.

McBride OW et al. (1987) A Taq I polymorphism in the human P450IIE1 gene on chromosome 10 (CYP2E).

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11.

Umeno M et al. (1988) Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression.

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12.

Okino ST et al. (1987) Characterization of multiple human cytochrome P-450 1 cDNAs. The chromosomal localization of the gene and evidence for alternate RNA splicing.

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13.

Song BJ et al. (1986) Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

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14.

None (1993) Regional mapping of short tandem repeats on human chromosome 10: cytochrome P450 gene CYP2E, D10S196, D10S220, and D10S225.

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15.

Tanaka F et al. (1997) Polymorphism of alcohol-metabolizing genes affects drinking behavior and alcoholic liver disease in Japanese men.

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Update: 23. Juni 2025
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